SCHEMBL7621666

SCHEMBL7621666

C=C(C)C(=O)OC(CC)OC(CC)OC(C)OC(C)Oc1ccc(C(C)(C)c2ccc(OC(C)OC(C)OC(CC)OC(CC)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AR P10275 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NR1H4 Q96RI1 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633691 0.95 KDM4E (0.37) KDM4EMEN1GAAHTTKMT2A
SCHEMBL7623767 0.89 AR (0.36) KDM4EMEN1GAAHTTKMT2A
SCHEMBL195039 0.87 KDM4E (0.41) KDM4EMEN1GAAHTTKMT2A
SCHEMBL17159499 0.86 KDM4E (0.37) KDM4EMEN1GAAHTTKMT2A
SCHEMBL9067297 0.85 AR (0.36) KDM4EMEN1GAAHTTKMT2A
SCHEMBL8957788 0.85 AR (0.36) KDM4EMEN1GAAHTTKMT2A
SCHEMBL8957729 0.85 AR (0.36) KDM4EMEN1GAAHTTKMT2A
SCHEMBL8957664 0.85 AR (0.36) KDM4EMEN1GAAHTTKMT2A
SCHEMBL8957644 0.85 AR (0.36) KDM4EMEN1GAAHTTKMT2A
SCHEMBL9071095 0.85 AR (0.36) KDM4EMEN1GAAHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US claimed
EP-0828167-B1 Resin composition for polymerization casting and optical material NOF CORP (JP) 2002-07-03 EP disclosed
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US disclosed
EP-0828167-A2 Resin composition for polymerization casting and optical material NOF CORPORATION (JP) 1998-03-11 EP disclosed