SCHEMBL7623767

SCHEMBL7623767

C=C(C)C(=O)OC(CC)OC(CC)OC(CC)Oc1ccc(C(C)(C)c2ccc(OC(CC)OC(CC)OC(CC)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.36
KDM4E B2RXH2 6/20 0.36
HTT P42858 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 5/20 0.32
TDP1 Q9NUW8 2/20 0.32
POLB P06746 2/20 0.32
HIF1A Q16665 1/20 0.32
NR1H4 Q96RI1 1/20 0.31
ELANE P08246 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
MAPT P10636 1/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL957304 0.92 AR (0.39) ARKDM4EHTTMEN1KMT2A
SCHEMBL7621666 0.89 KDM4E (0.35) ARKDM4EHTTMEN1KMT2A
SCHEMBL7633691 0.89 KDM4E (0.37) ARKDM4EHTTMEN1KMT2A
SCHEMBL17159499 0.89 KDM4E (0.37) ARKDM4EHTTMEN1KMT2A
SCHEMBL9517525 0.84 ALDH1A1 (0.36) ARKDM4EHTTMEN1KMT2A
SCHEMBL7625525 0.84 THRB (0.36) ARKDM4EHTTMEN1KMT2A
SCHEMBL195096 0.83 KDM4E (0.43) ARKDM4EHTTMEN1KMT2A
SCHEMBL17159501 0.80 THRB (0.39) ARKDM4EHTTMEN1KMT2A
SCHEMBL195039 0.80 KDM4E (0.41) ARKDM4EHTTMEN1KMT2A
SCHEMBL28402128 0.80 KDM4E (0.42) KDM4EHTTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US claimed
EP-0828167-B1 Resin composition for polymerization casting and optical material NOF CORP (JP) 2002-07-03 EP disclosed
US-5942303-A CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES NOF CORPORATION (JP) 1999-08-24 US disclosed
EP-0828167-A2 Resin composition for polymerization casting and optical material NOF CORPORATION (JP) 1998-03-11 EP disclosed