Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 19/20 | 1.00 |
| ▸ | MME | P08473 | 17/20 | 1.00 |
| ▸ | ACE | P12821 | 2/20 | 0.74 |
| ▸ | MMP13 | P45452 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925939 | 0.94 | ECE1 (0.88) | ECE1MME | |
| SCHEMBL6926704 | 0.91 | ECE1 (0.86) | ECE1MME | |
| SCHEMBL6928069 | 0.89 | ACE2 (0.81) | ECE1MME | |
| SCHEMBL6924974 | 0.88 | ECE1 (1.00) | ECE1MME | |
| SCHEMBL6927544 | 0.86 | ECE1 (0.88) | ECE1MME | |
| SCHEMBL6922969 | 0.86 | ECE1 (0.91) | ECE1MMEACE | |
| SCHEMBL7615297 | 0.86 | ECE1 (0.76) | ECE1MMEACE | |
| SCHEMBL3862234 | 0.86 | ECE1 (1.00) | ECE1MMEACEMMP13 | |
| SCHEMBL3866175 | 0.86 | ECE1 (1.00) | ECE1MMEACEMMP13 | |
| SCHEMBL4876681 | 0.86 | ECE1 (1.00) | ECE1MMEACEMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009750-B1 | NOVEL (ALPHA-AMINOPHOSPHINO) PEPTIDE DERIVATIVES, METHOD FOR MAKING SAME AND THERAPEUTIC APPLICATIONS THEREOF | INST NAT SANTE RECH MED (FR) | 2002-07-31 | — | — | EP | disclosed |