Sugi Predict

Sugi Predict / Compounds / SCHEMBL6925939

SCHEMBL6925939

SCHEMBL6925939

O=C(NC(Cc1ccccc1)P(=O)(O)CC(Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.88

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 19/20 0.88
▸ MME P08473 17/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621700 0.94 ECE1 (1.00) ECE1MME
SCHEMBL6927137 0.90 ECE1 (0.72) ECE1MME
SCHEMBL6927544 0.88 ECE1 (0.88) ECE1MME
SCHEMBL6928069 0.87 ACE2 (0.81) ECE1MME
SCHEMBL6924974 0.86 ECE1 (1.00) ECE1MME
SCHEMBL6926717 0.86 ECE1 (0.78) ECE1MME
SCHEMBL6928745 0.85 ECE1 (0.77) ECE1MME
SCHEMBL6926704 0.85 ECE1 (0.86) ECE1MME
SCHEMBL6922969 0.84 ECE1 (0.91) ECE1MME
SCHEMBL7615297 0.84 ECE1 (0.76) ECE1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518260-B1 (α-aminophosphino) peptide derivatives, method for making same and therapeutic applications thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2003-02-11 — — US disclosed