Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.61 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614088 | 1.00 | TBXAS1 (0.61) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL7623524 | 0.98 | TBXAS1 (0.58) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL7616768 | 0.95 | TBXAS1 (0.54) | TBXAS1F13A1MAPTRXFP1LMNA | |
| SCHEMBL7617937 | 0.87 | TBXAS1 (0.45) | TBXAS1MAPTRXFP1 | |
| SCHEMBL7625592 | 0.86 | TBXAS1 (0.45) | TBXAS1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7620248 | 0.81 | HPGD (0.43) | TBXAS1MAPTLMNATSHR | |
| SCHEMBL7618079 | 0.81 | TBXAS1 (0.41) | TBXAS1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7623365 | 0.79 | TSHR (0.42) | TBXAS1MAPTLMNATSHR | |
| SCHEMBL7623376 | 0.79 | CYP4F2 (0.46) | TBXAS1MAPTTSHR | |
| SCHEMBL7623156 | 0.77 | MEN1 (0.47) | TBXAS1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |