Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623156 | 0.84 | MEN1 (0.47) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7622600 | 0.84 | MEN1 (0.47) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7622667 | 0.84 | MEN1 (0.47) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7625860 | 0.83 | CNR1 (0.43) | MTNR1AFAAH | |
| SCHEMBL7625592 | 0.81 | TBXAS1 (0.45) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7614088 | 0.81 | TBXAS1 (0.61) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7621773 | 0.81 | TBXAS1 (0.61) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7623365 | 0.80 | TSHR (0.42) | TBXAS1 | |
| SCHEMBL7623524 | 0.79 | TBXAS1 (0.58) | TBXAS1HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL4873532 | 0.77 | TSHR (0.42) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |