Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 6/20 | 0.39 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.39 |
| ▸ | INPP5B | P32019 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613747 | 0.87 | ESR1 (0.44) | TYRINPPL1INPP5AINPP5BAKT1 | |
| SCHEMBL6396289 | 0.85 | ADRB1 (0.42) | TYRINPPL1INPP5AINPP5BADRB1 | |
| SCHEMBL7615265 | 0.84 | SLC22A1 (0.40) | TYRINPPL1INPP5AINPP5BADRB1 | |
| SCHEMBL7618814 | 0.83 | INPPL1 (0.38) | INPPL1INPP5AINPP5BADRB1ADRA1A | |
| SCHEMBL6397897 | 0.82 | HIF1A (0.38) | INPPL1INPP5AINPP5BADRB1ADRA1A | |
| SCHEMBL7622158 | 0.81 | INPPL1 (0.35) | INPPL1INPP5AINPP5BADRB1ADRA1A | |
| SCHEMBL6397848 | 0.80 | OPRM1 (0.42) | INPPL1INPP5AINPP5BADRB1ADRA1A | |
| SCHEMBL7622944 | 0.80 | INPPL1 (0.41) | TYRINPPL1INPP5AINPP5BADRB1 | |
| SCHEMBL6395800 | 0.79 | INPPL1 (0.36) | INPPL1INPP5AINPP5BADRB1ADRA1A | |
| SCHEMBL7621447 | 0.79 | INPPL1 (0.36) | INPPL1INPP5AINPP5BADRB1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175425-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000043402-A2 | INHIBITORS OF INTESTINAL APICAL MEMBRANE NA/PHOSPHATE CO-TRANSPORTATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-27 | — | — | WO | disclosed |