Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063313 | 0.94 | CYP4A11 (0.51) | CYP4A11CYP4F2LOXL2NPC1RAB9A | |
| SCHEMBL24843670 | 0.91 | LOXL2 (0.53) | CYP4A11CYP4F2LOXL2NPC1RAB9A | |
| SCHEMBL23866983 | 0.86 | LOXL2 (0.51) | CYP4A11CYP4F2LOXL2NPC1RAB9A | |
| SCHEMBL13543623 | 0.84 | LOXL2 (0.56) | CYP4A11CYP4F2LOXL2NPC1RAB9A | |
| SCHEMBL2653884 | 0.81 | LOXL2 (0.56) | CYP4A11CYP4F2LOXL2NPC1MAPT | |
| SCHEMBL14379749 | 0.80 | LOXL2 (0.51) | CYP4A11CYP4F2LOXL2NPC1RAB9A | |
| SCHEMBL28295886 | 0.80 | LOXL2 (0.54) | CYP4A11CYP4F2LOXL2NPC1RAB9A | |
| SCHEMBL12112442 | 0.79 | TSHR (0.56) | NPC1RAB9ACASP1MGLLMAPT | |
| SCHEMBL9723713 | 0.79 | MAPT (0.46) | NPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL16523044 | 0.79 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216222-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019776-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |