Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614719 | 0.88 | CYP4A11 (0.50) | LOXL2CYP4A11CYP4F2NPC1RAB9A | |
| SCHEMBL7622296 | 0.86 | CYP4A11 (0.54) | LOXL2CYP4A11CYP4F2NPC1RAB9A | |
| SCHEMBL25336125 | 0.86 | CYP4A11 (0.44) | LOXL2CYP4A11CYP4F2NPC1RAB9A | |
| SCHEMBL25464956 | 0.84 | LOXL2 (0.51) | LOXL2CYP4A11CYP4F2NPC1RAB9A | |
| SCHEMBL6653642 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4HSD17B10CA2 | |
| SCHEMBL28867145 | 0.82 | MGLL (0.40) | LOXL2CYP4A11CYP4F2NPC1RAB9A | |
| SCHEMBL19717723 | 0.81 | TSHR (0.42) | ALDH1A1LMNACYP3A4HSD17B10MAPT | |
| SCHEMBL28063313 | 0.81 | CYP4A11 (0.51) | LOXL2CYP4A11CYP4F2NPC1RAB9A | |
| SCHEMBL10800514 | 0.80 | ALDH1A1 (0.49) | CYP4A11CYP4F2ALDH1A1LMNACYP3A4 | |
| SCHEMBL6658753 | 0.80 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | UNIV TEXAS (US) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | LOXL2 3192/4885CYP4A11 3291/4885CYP4F2 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.