Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618726 | 0.88 | ACHE (0.52) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL7616686 | 0.81 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL7615988 | 0.80 | KMT2A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7712023 | 0.77 | GRM4 (0.46) | KMT2AMEN1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL6130205 | 0.77 | KMT2A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14754995 | 0.77 | KMT2A (0.62) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL460134 | 0.77 | MAPT (0.48) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL6130227 | 0.76 | KMT2A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11349950 | 0.75 | KMT2A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28388459 | 0.75 | KMT2A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110540552-A | Aromatic phosphorus oxide compound and preparation method of aromatic phosphorus oxide medicine thereof | UNIV HUNAN | 2019-12-06 | — | — | CN | disclosed |
| EP-0926152-B1 | Process for the manufacture of bis(phosphine oxide)-and bis(phosphonate)-compounds | HOFFMANN LA ROCHE (CH) | 2002-09-11 | — | — | EP | disclosed |
| US-6162929-A | Process for the manufacture of bisphosphine oxide and bisphosphonate compounds | HOFFMANN-LA ROCHE INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-0926152-A1 | Process for the manufacture of bis(phosphine oxide)-and bis(phosphonate)-compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-30 | — | — | EP | disclosed |