Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712023 | 0.84 | GRM4 (0.46) | KMT2AHTTL3MBTL1LMNAMEN1 | |
| SCHEMBL7622693 | 0.81 | TUBB4A (0.49) | KMT2AHTTL3MBTL1CYP1A2MEN1 | |
| SCHEMBL28453272 | 0.78 | L3MBTL1 (0.44) | KMT2AHTTL3MBTL1CYP1A1CYP1A2 | |
| SCHEMBL14754995 | 0.77 | KMT2A (0.62) | KMT2AHTTL3MBTL1LMNAMEN1 | |
| SCHEMBL5619254 | 0.76 | CA4 (0.54) | KMT2AHTTLMNAMEN1NPC1 | |
| SCHEMBL5619896 | 0.76 | CA4 (0.54) | KMT2AHTTLMNAMEN1NPC1 | |
| SCHEMBL7619840 | 0.76 | LMNA (0.50) | KMT2AHTTL3MBTL1LMNAMEN1 | |
| SCHEMBL11225829 | 0.75 | CA2 (0.45) | KMT2AHTTL3MBTL1CYP1A2LMNA | |
| SCHEMBL10723400 | 0.75 | CA2 (0.45) | KMT2AHTTL3MBTL1CYP1A2LMNA | |
| SCHEMBL4406229 | 0.75 | TSHR (0.48) | KMT2AL3MBTL1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926152-B1 | Process for the manufacture of bis(phosphine oxide)-and bis(phosphonate)-compounds | HOFFMANN LA ROCHE (CH) | 2002-09-11 | — | — | EP | disclosed |
| US-6162929-A | Process for the manufacture of bisphosphine oxide and bisphosphonate compounds | HOFFMANN-LA ROCHE INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-0926152-A1 | Process for the manufacture of bis(phosphine oxide)-and bis(phosphonate)-compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-30 | — | — | EP | disclosed |
| US-5488172-A | Chiral phosphorus compounds | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0398132-B1 | Phosphorous compounds | HOFFMANN LA ROCHE (CH) | 1995-09-20 | — | — | EP | disclosed |
| EP-0398132-A2 | Phosphorous compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1990-11-22 | — | — | EP | disclosed |