Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 4/20 | 0.47 |
| ▸ | CASP9 | P55211 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | CASP4 | P49662 | 2/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.44 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628542 | 0.87 | CASP3 (0.45) | CASP3CASP1CASP9CASP7SIRT2 | |
| SCHEMBL7112627 | 0.85 | CASP3 (0.58) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL3692638 | 0.85 | CASP3 (0.58) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL3140616 | 0.85 | CASP3 (0.62) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL614741 | 0.85 | CASP3 (0.62) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL3692630 | 0.84 | CASP3 (0.56) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL18740358 | 0.82 | CASP3 (0.58) | CASP3CASP1CASP9CASP7CASP4 | |
| SCHEMBL7383742 | 0.81 | CASP3 (0.67) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL4420464 | 0.81 | CASP3 (0.67) | CASP3CASP1CASP9CASP7MME | |
| SCHEMBL24213871 | 0.80 | CASP3 (0.56) | CASP3CASP1CASP9CASP7CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100528-B1 | USE OF NOVEL AGENTS INDUCING CELL DEATH IN SYNERGY WITH INTERFERONS | INST NAT SANTE RECH MED (FR) | 2002-10-16 | — | — | EP | disclosed |
| EP-1100528-A2 | USE OF NOVEL AGENTS INDUCING CELL DEATH IN SYNERGY WITH INTERFERONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007616-A2 | USE OF NOVEL AGENTS INDUCING CELL DEATH IN SYNERGY WITH INTERFERONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-02-17 | — | — | WO | disclosed |