Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 12/20 | 0.58 |
| ▸ | CASP1 | P29466 | 7/20 | 0.55 |
| ▸ | CASP7 | P55210 | 7/20 | 0.54 |
| ▸ | CASP9 | P55211 | 4/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | CASP4 | P49662 | 3/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.50 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | CASP5 | P51878 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112627 | 1.00 | CASP3 (0.58) | CASP3CASP1CASP7CASP9MME | |
| SCHEMBL614741 | 0.96 | CASP3 (0.62) | CASP3CASP1CASP7CASP9MME | |
| SCHEMBL3140616 | 0.96 | CASP3 (0.62) | CASP3CASP1CASP7CASP9MME | |
| SCHEMBL17803368 | 0.93 | CASP3 (0.55) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL3692630 | 0.92 | CASP3 (0.56) | CASP3CASP1CASP7CASP9MME | |
| SCHEMBL4420464 | 0.92 | CASP3 (0.67) | CASP3CASP1CASP7CASP9MME | |
| SCHEMBL7383742 | 0.92 | CASP3 (0.67) | CASP3CASP1CASP7CASP9MME | |
| SCHEMBL18740358 | 0.91 | CASP3 (0.58) | CASP3CASP1CASP7CASP9CASP4 | |
| SCHEMBL3488773 | 0.89 | CASP1 (0.71) | CASP3CASP1CASP7CASP9REN | |
| SCHEMBL29453232 | 0.88 | MME (0.58) | CASP3CASP1MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120207730-A1 | Methods and Compositions for Treating Viral Hemorrhagic Fever | NATIONAL TAIWAN UNIVERSITY (TW) | 2012-08-16 | — | — | US | disclosed |
| US-20100080807-A1 | Methods and Compositions for Treating Viral Hemorrhagic Fever | NATIONAL TAIWAN UNIVERSITY (TW) | 2010-04-01 | — | — | US | disclosed |