Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 13/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830319 | 1.00 | ADAMTS5 (0.50) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL762368 | 1.00 | ADAMTS5 (0.50) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| D-Glutamate SCHEMBL11414446 | 0.86 | GRM8 (0.53) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL1679984 | 0.83 | NPSR1 (0.50) | ADAMTS5ADAMTS4NPSR1TDP1ABL1 | |
| SCHEMBL31707085 | 0.83 | NPSR1 (0.50) | ADAMTS5ADAMTS4NPSR1TDP1ABL1 | |
| SCHEMBL13803876 | 0.82 | ADAMTS5 (0.46) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL18123425 | 0.82 | GAA (0.46) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL17819214 | 0.82 | ADAMTS5 (0.46) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL13176600 | 0.82 | ADAMTS5 (0.46) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 | |
| SCHEMBL17819216 | 0.82 | ADAMTS5 (0.46) | ADAMTS5ADAMTS4ADAM17ADAM10MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121577769-A | Urine metabolism marker composition for diagnosing kidney cancer and application thereof | 哈尔滨脉图精准技术有限公司 | 2026-02-27 | — | — | CN | claimed |
| WO-2025123045-A1 | PREDICTIVE AND DIAGNOSTIC SCREENING METHODS FOR ENDOMETRIAL CANCER | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-06-12 | — | — | WO | claimed |
| EP-4537111-A2 | MULTI-OMICS ASSESSMENT | Prognomiq Inc (US) | 2025-04-16 | — | — | EP | claimed |
| CN-119816897-A | Multiple study assessment | 普罗科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| US-12050228-B2 | Automated sample quality assessment | METABOLON, INC. (US) | 2024-07-30 | — | — | US | claimed |
| CN-117990922-A | Metabolic marker for diabetes combined coronary heart disease diagnosis and application | 哈尔滨脉图精准技术有限公司 | 2024-05-07 | — | — | CN | claimed |
| WO-2023240046-A2 | MULTI-OMICS ASSESSMENT | PrognomIQ, Inc. (US) | 2023-12-14 | — | — | WO | claimed |
| EP-3796976-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO THE QUALITY OF AGING AND LONGEVITY | Epitracker, Inc. (US) | 2021-03-31 | — | — | EP | claimed |
| US-20210088539-A1 | AUTOMATED SAMPLE QUALITY ASSESSMENT | METABOLON, INC. | 2021-03-25 | — | — | US | claimed |
| US-10890592-B2 | Automated sample quality assessment | METABOLON, INC. (US) | 2021-01-12 | — | — | US | claimed |
| US-20050112729-A1 | Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid | AJINOMOTO CO., INC. (JP) | 2005-05-26 | — | — | US | claimed |
| US-5995869-A | Reduction of skin sensitization in electrotransport drug delivery | ALZA CORPORATION (US) | 1999-11-30 | — | — | US | claimed |
| US-5912010-A | ADMINISTERING LOOP DIURETIC ALONE OR WITH MAST CELL DEGRANULATOR OR GLUCOCORTICOSTEROID | E.R. SQUIBB & SONS, INC. (US) | 1999-06-15 | — | — | US | claimed |
| US-5843979-A | Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-01 | — | — | US | claimed |
| WO-1997047355-A1 | REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY | ALZA CORPORATION (US) | 1997-12-18 | — | — | WO | claimed |
| US-5686100-A | Prophylactic and therapeutic treatment of skin sensitization and irritation | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | claimed |
| EP-0612525-A1 | Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-08-31 | — | — | EP | claimed |
| US-5338859-A | Reacting a hydantoin with a calcium base; crystallization; precipitation; separation | HOECHST CELANESE CORPORATION (US) | 1994-08-16 | — | — | US | claimed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-4082767-A | CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-04 | — | — | US | claimed |