Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | APAF1 | O14727 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7623772 | 0.87 | LMNA (0.63) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL26184983 | 0.86 | LMNA (0.61) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL970698 | 0.85 | HSP90AA1 (0.60) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL969011 | 0.85 | HSP90AA1 (0.60) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL6906934 | 0.85 | HSP90AA1 (0.60) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL971801 | 0.84 | MEN1 (0.57) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL973743 | 0.84 | MEN1 (0.57) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6911434 | 0.84 | MEN1 (0.57) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL970219 | 0.83 | MEN1 (0.56) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL969985 | 0.83 | MEN1 (0.56) | LMNAHSP90AA1APAF1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436890-B1 | Antimicrobial detergent composition | INUI CORPORATION (JP) | 2002-08-20 | — | — | US | claimed |
| EP-1092763-A2 | Antimicrobial detergent composition | Inui Corporation (JP) | 2001-04-18 | — | — | EP | claimed |
| US-6436890-B1 | Antimicrobial detergent composition | INUI CORPORATION (JP) | 2002-08-20 | — | — | US | disclosed |
| EP-1092763-A2 | Antimicrobial detergent composition | Inui Corporation (JP) | 2001-04-18 | — | — | EP | disclosed |