Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | APAF1 | O14727 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26184983 | 0.99 | LMNA (0.61) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| Bromide SCHEMBL10582124 | 0.89 | LMNA (0.57) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| Bromide SCHEMBL7623764 | 0.87 | LMNA (0.60) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| SCHEMBL2761500 | 0.86 | LMNA (0.48) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| Bromide SCHEMBL969012 | 0.85 | MAPK1 (0.63) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| Bromide SCHEMBL970700 | 0.85 | MAPK1 (0.63) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| Bromide SCHEMBL6906938 | 0.85 | MAPK1 (0.63) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| SCHEMBL1573921 | 0.83 | GLA (0.63) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 | |
| SCHEMBL10257278 | 0.82 | LMNA (0.57) | LMNAALDH1A1TSHRNPC1MAPT | |
| Hydrochloric Acid SCHEMBL973745 | 0.82 | ALDH1A1 (0.61) | LMNAHSP90AA1ALDH1A1APAF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436890-B1 | Antimicrobial detergent composition | INUI CORPORATION (JP) | 2002-08-20 | — | — | US | claimed |
| EP-1092763-A2 | Antimicrobial detergent composition | Inui Corporation (JP) | 2001-04-18 | — | — | EP | claimed |
| US-6436890-B1 | Antimicrobial detergent composition | INUI CORPORATION (JP) | 2002-08-20 | — | — | US | disclosed |
| EP-1092763-A2 | Antimicrobial detergent composition | Inui Corporation (JP) | 2001-04-18 | — | — | EP | disclosed |