Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625531 | 0.83 | KDM4E (0.46) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7622862 | 0.79 | KDM4E (0.37) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28498647 | 0.78 | ACACB (0.50) | KDM4EPOLBALDH1A1HTTACACB | |
| SCHEMBL10375214 | 0.77 | HTT (0.39) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| Propane SCHEMBL9476274 | 0.76 | HTT (0.53) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL14173142 | 0.75 | POLB (0.56) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL59813 | 0.75 | POLB (0.56) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL19327020 | 0.75 | ABCB11 (0.33) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL346370 | 0.74 | POLB (0.62) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7631159 | 0.74 | ACACB (0.41) | KDM4EPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | claimed |
| EP-0828167-B1 | Resin composition for polymerization casting and optical material | NOF CORP (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0828167-A2 | Resin composition for polymerization casting and optical material | NOF CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |