Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.32 |
| ▸ | RARG | P13631 | 6/20 | 0.32 |
| ▸ | RARA | P10276 | 3/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406365 | 0.95 | RARB (0.34) | RARBRARGRARARXRARXRB | |
| SCHEMBL30175873 | 0.84 | — | — | |
| SCHEMBL1818812 | 0.84 | — | — | |
| SCHEMBL24084730 | 0.75 | RXRA (0.33) | RARBRARGRARARXRARXRB | |
| SCHEMBL21776849 | 0.75 | CYP26A1 (0.35) | RARBRARGRARARXRARXRB | |
| SCHEMBL29605516 | 0.75 | CYP26A1 (0.35) | RARBRARGRARARXRARXRB | |
| SCHEMBL29873435 | 0.72 | RARB (0.40) | RARBRARGRARARXRARXRB | |
| SCHEMBL21776799 | 0.72 | RARB (0.40) | RARBRARGRARARXRARXRB | |
| SCHEMBL18009559 | 0.67 | — | — | |
| SCHEMBL14156956 | 0.67 | PDK2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062219-B1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | DOW CHEMICAL CO (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | disclosed |
| US-6127563-A | PREPARING BRIDGED GROUP 4 METAL COMPLEXES CONTAINING A NEUTRAL DIENE LIGAND STARTING FROM THE CORRESPONDING NOVEL, METAL DIENE CONTAINING COMPLEXES BY REACTION THEREOF WITH THE DIVALENT DERIVATIVE OF A BRIDGED BIDENTATE LIGAND COMPOUND | THE DOW CHEMICAL COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| US-6084115-A | METAL DIENE-CONTAINING COMPLEXES BY REACTION WITH THE DIVALENT DERIVATIVE OF A BRIDGED BIDENTATE LIGAND; METALLOCENES; RACEMIC ISOMER USED TO PREPARE ISOTACTIC POLYOLEFINS, E.G., CRYSTALLINE POLYPROPYLENE. | THE DOW CHEMICAL COMPANY (US) | 2000-07-04 | — | — | US | disclosed |