Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298713 | 0.91 | TYR (0.58) | ALOX15TYRUSP2GAARAD51 | |
| SCHEMBL31375351 | 0.91 | TYR (0.58) | ALOX15TYRUSP2GAARAD51 | |
| SCHEMBL48994 | 0.91 | TYR (0.58) | ALOX15TYRUSP2GAARAD51 | |
| SCHEMBL31375356 | 0.91 | TYR (0.58) | ALOX15TYRUSP2GAARAD51 | |
| Bromide SCHEMBL27546379 | 0.89 | TYR (0.56) | ALOX15TYRUSP2GAARAD51 | |
| Bromide SCHEMBL29769307 | 0.89 | TYR (0.56) | ALOX15TYRUSP2GAARAD51 | |
| Hydrochloric Acid SCHEMBL4625112 | 0.89 | TYR (0.56) | ALOX15TYRUSP2GAARAD51 | |
| SCHEMBL5464095 | 0.83 | KDM4E (0.43) | ALOX15TYRUSP2GAARAD51 | |
| Bicarbonate SCHEMBL4385266 | 0.83 | ENPP2 (0.53) | ALOX15TYRUSP2GAARAD51 | |
| Sulfuric Acid SCHEMBL9312939 | 0.82 | TYR (0.48) | ALOX15TYRUSP2GAARAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440691-B1 | AIDS VIRICIDES | LARGE SCALE BIOLOGY CORPORATION | 2002-08-27 | — | — | US | disclosed |
| US-20020039726-A1 | Melanins with improved ability to inhibit HIV replication | GARGER STEVEN (US) | 2002-04-04 | — | — | US | disclosed |
| US-6300057-B1 | TREATING HIV INFECTIONS BY ADMINISTERING A THERAPEUTIC DOSE OF SYNTHESIZED MELANIN CONTAINING AN ANIONIC GROUP OF SULFATES AND SULFONYLS; NONTOXIC THERAPY OF HUMAN IMMUNODEFICIENCY VIRUS | LARGE SCALE BIOLOGY CORPORATION | 2001-10-09 | — | — | US | disclosed |
| EP-1096021-A2 | Melanins with improved ability to inhibit HIV replication | Biosource Technologies, Inc. (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-1095652-A2 | Melanins with improved ability to inhibit HIV replication | Biosource Technologies, Inc. (US) | 2001-05-02 | — | — | EP | disclosed |
| US-5801047-A | Method for making stable extracellular tyrosinase and synthesis of polyphenolic polymers therefrom | BIOSOURCE TECHNOLOGIES, INC. (US) | 1998-09-01 | — | — | US | disclosed |
| US-5792649-A | IN VITRO CULTURE MEDIUM CONTAINING MICROORGANISM EXPRESSING TYROSINASE HAVING ACTIVITY STABILIZED BY A REDUCED CONCENTRATION OF DISSOLVED OXYGEN IN THE MEDIUM | BIOSOURCE TECHNOLOGIES, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| US-5486351-A | MELANINS | BIOSOURCE TECHNOLOGIES, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| US-5466592-A | Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom | BIOSOURCE TECHNOLOGIES, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0672148-A1 | METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM | Biosource Technologies, Inc. (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5340734-A | In vitro biosynthesis the melanins in presence of a substrate consisting of tyrosine binding single amino acid, a dipeptide or an oligopeptide | BIOSOURCE GENETICS CORPORATION (US) | 1994-08-23 | — | — | US | disclosed |
| WO-1994012644-A2 | METHOD FOR MAKING STABLE, EXTRACELLULAR TYROSINASE AND SYNTHESIS OF POLYPHENOLIC POLYMERS THEREFROM | BIOSOURCE GENETICS CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |