SCHEMBL48994

SCHEMBL48994

Oc1cc2cc[nH]c2cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.58
USP2 O75604 1/20 0.58
GAA P10253 1/20 0.58
ALOX15 P16050 1/20 0.58
RAD51 Q06609 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
GPR84 Q9NQS5 1/20 0.54
ENPP2 Q13822 2/20 0.47
CSNK2A1 P68400 1/20 0.47
AHR P35869 7/20 0.46
CYP2A6 P11509 3/20 0.46
NR4A2 P43354 2/20 0.46
CMA1 P23946 1/20 0.46
F7 P08709 1/20 0.46
LTA4H P09960 1/20 0.46
F3 P13726 1/20 0.46
GUSB P08236 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31375351 1.00 TYR (0.58) TYRUSP2GAAALOX15RAD51
SCHEMBL31375356 1.00 TYR (0.58) TYRUSP2GAAALOX15RAD51
SCHEMBL28298713 1.00 TYR (0.58) TYRUSP2GAAALOX15RAD51
Bromide SCHEMBL29769307 0.98 TYR (0.56) TYRUSP2GAAALOX15RAD51
Hydrochloric Acid SCHEMBL4625112 0.98 TYR (0.56) TYRUSP2GAAALOX15RAD51
Bromide SCHEMBL27546379 0.98 TYR (0.56) TYRUSP2GAAALOX15RAD51
Catechol SCHEMBL7624422 0.91 ALOX15 (0.50) TYRUSP2GAAALOX15RAD51
Bicarbonate SCHEMBL4385266 0.91 ENPP2 (0.53) TYRUSP2GAAALOX15RAD51
Sulfuric Acid SCHEMBL9312939 0.89 TYR (0.48) TYRUSP2GAAALOX15RAD51
SCHEMBL7580262 0.89 TYR (0.48) TYRUSP2GAAALOX15RAD51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6499 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105476-A1 METHOD FOR PRODUCING PROCESSED FIBERS 花王株式会社 2026-05-21 WO claimed
WO-2026105475-A1 METHOD FOR PRODUCING PROCESSED FIBERS 花王株式会社 2026-05-21 WO claimed
CN-122056785-A Solid hair dyeing composition based on 5, 6-dihydroxyindole and preparation method thereof 杭州湘莱生物科技有限公司 2026-05-19 CN claimed
CN-122031292-A Active component for hair dye and preparation method thereof 四川中科兴业高新材料有限公司 2026-05-15 CN claimed
CN-122031279-A Hair dyeing composition based on hydrogen peroxide and preparation method thereof 四川中科兴业高新材料有限公司 2026-05-15 CN claimed
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR DR. KURT WOLFF GMBH & CO. KG (DE) 2026-04-09 US claimed
WO-2026047185-A1 AGENT FOR DYEING KERATIN FIBERS DR. KURT WOLFF GMBH & CO. KG (DE) 2026-03-05 WO claimed
EP-4702967-A1 CONDITIONER FOR KERATIN FIBRES Dr. Kurt Wolff GmbH & Co. KG (DE) 2026-03-04 EP claimed
EP-4702969-A1 AGENT FOR DYEING KERATIN FIBRES Dr. Kurt Wolff GmbH & Co. KG (DE) 2026-03-04 EP claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
EP-0342034-A2 Process for dyeing hair by the sequential treatment with metal ion containing composition and dye composition containing 5,6-dihydroxyindole-2-carboxylic acid Bristol-Myers Squibb Company (US) 1989-11-15 EP claimed
EP-0337853-A1 Procedure of the preversation of the dyeing ability of 5,6-dihydroxy-indole and its derivatives in an aqueous milieu, composition and procedure of dyeing L'OREAL (FR) 1989-10-18 EP claimed
EP-0335477-A2 The use of N-substituted-5,6-dihydroxyindoles as a hair coloring agent Bristol-Myers Squibb Company (US) 1989-10-04 EP claimed
US-4808190-A Process for dyeing keratinous fibres with 5,6-dihydroxy-indole and hydrogen peroxide, preceded or followed by a treatment with an iodide L'OREAL (FR) 1989-02-28 US claimed
US-4804385-A Process for dyeing keratinous fibres with 5,6-dihydroxy-indole combined with an iodide and dyeing composition employed L'OREAL (FR) 1989-02-14 US claimed
CN-88101714-A With being mixed with 5 of iodide ion, 6-oxyindole and alkaline pH hydrogen peroxide composition carry out the method for dyeing keratinous fibres 1988-10-19 CN claimed
CN-87107372-A Process for preparing 5, 6-dihydroxyindoles and 3-alkyl derivatives and intermediate compounds thereof 1988-08-03 CN claimed
CN-87100820-A With bonded 5 with iodide, the colouring compositions that the 6-dihydroxy indole carries out painted method and adopted keratin fiber 1987-10-28 CN claimed
US-4595765-A Process for preparing 5,6-dihydroxyindole CLAIROL INCORPORATED (US) 1986-06-17 US claimed
US-4208183-A DISSOLVING IN AN ANHYDROUS HYDROXYLIC SOLVENT L'OREAL (FR) 1980-06-17 US claimed