⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643317 | 1.00 | — | — | |
| SCHEMBL7662496 | 0.82 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL7659302 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL4405125 | 0.78 | — | — | |
| SCHEMBL5283640 | 0.77 | CYP1A2 (0.36) | — | |
| SCHEMBL7013311 | 0.76 | — | — | |
| SCHEMBL17224585 | 0.76 | — | — | |
| SCHEMBL13498357 | 0.76 | — | — | |
| SCHEMBL12449150 | 0.76 | MEN1 (0.36) | — | |
| SCHEMBL265958 | 0.76 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101684078-B | Chemical synthesis method for of 2-amino-butanamide hydrochloride | UNIV ZHEJIANG TECHNOLOGY | 2013-01-16 | — | — | CN | claimed |
| CN-101684078-A | Chemical synthesis method for of 2-amino-butanamide hydrochloride | UNIV ZHEJIANG TECHNOLOGY | 2010-03-31 | — | — | CN | claimed |
| US-20260125388-A1 | GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL SMOOTH MUSCLE CONTRACTION AND INFLAMMATION | UWM RES FOUNDATION INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2024077061-A2 | GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL SMOOTH MUSCLE CONTRACTION AND INFLAMMATION | UWM RESEARCH FOUNDATION, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| CN-105198768-B | A kind of synthetic method of 2 amino-butanamide | 江苏中邦制药有限公司 | 2017-07-04 | — | — | CN | disclosed |
| US-9458182-B2 | Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| CN-105646265-A | Method for synthesizing (S)-2-aminobutanamide | 江苏中邦制药有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105198768-A | Synthesis method for 2-aminobutanamide | JIANGSU ZHONGBANG PHARMACEUTICAL CO LTD | 2015-12-30 | — | — | CN | disclosed |
| US-9067919-B2 | Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-8791226-B2 | Preparation of low molecular weight polyornithine in high yield | SIGMA-ALDRICH CO. LLC (US) | 2014-07-29 | — | — | US | disclosed |
| US-20130172517-A1 | PREPARATION OF LOW MOLECULAR WEIGHT POLYORNITHINE IN HIGH YIELD | SIGMA-ALDRICH CO. LLC (US) | 2013-07-04 | — | — | US | disclosed |
| CN-101684078-A | Chemical synthesis method for of 2-amino-butanamide hydrochloride | UNIV ZHEJIANG TECHNOLOGY | 2010-03-31 | — | — | CN | disclosed |
| US-7317070-B1 | Process for the preparation of polyamino acids | SIGMA-ALDRICH CO. (US) | 2008-01-08 | — | — | US | disclosed |
| US-6552029-B1 | For therapy of rheumatoid arthritis, psoriasis, graft v. host disease, asthma, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, complications following percutaneous transluminal coronary angioplasty, thrombosis | CELLTECH R&D LIMITED (GB) | 2003-04-22 | — | — | US | disclosed |
| EP-0934304-B1 | 2-PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LTD (GB) | 2003-02-26 | — | — | EP | disclosed |
| US-20020058819-A1 | METHOD OF PRODUCING 2,4-OXAZOLIDINEDIONES AND METAL SALTS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-05-16 | — | — | US | disclosed |
| US-6384231-B1 | CYCLIZATION OF 2 HYDROXYCARBOXYLATE WITH UREA; METAL ALKOXIDE; AROMATIC HYDROCARBON SOLVENT; BY-PRODUCT INHIBITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-07 | — | — | US | disclosed |
| US-6114333-A | 2-Pyrimidineamine derivatives and processes for their preparation | CELLTECH THERAPEUTICS LTD. (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934304-A1 | 2-PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998018782-A1 | 2-PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1998-05-07 | — | — | WO | disclosed |