SCHEMBL7659302

SCHEMBL7659302

CCCCC1NC(=O)OC1=O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
TP53 P04637 1/20 0.38
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.30
HLCS P50747 1/20 0.30
CYP1A2 P05177 3/20 0.30
MMP1 P03956 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5283640 0.94 CYP1A2 (0.36) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL2007688 0.92 CYP1A2 (0.39) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL20448811 0.92 CYP1A2 (0.39) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL7662496 0.88 SMN1; SMN2 (0.34) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL23219623 0.79 DAO (0.30)
SCHEMBL762450 0.79
SCHEMBL1643317 0.79
SCHEMBL31055607 0.78 TERT (0.38)
SCHEMBL13661709 0.78 SIGMAR1 (0.33)
SCHEMBL14671140 0.77 PRKCA (0.40) ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7205385-B2 magnetic resonance imaging agents; poly(amino acid-imaging agent) product can be obtained in high purity without a rigorous purification since all impurities are removed at the monomer synthesis stage GENERAL ELECTRIC COMPANY (US) 2007-04-17 US disclosed
US-20020058819-A1 METHOD OF PRODUCING 2,4-OXAZOLIDINEDIONES AND METAL SALTS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED 2002-05-16 US disclosed
US-6384231-B1 CYCLIZATION OF 2 HYDROXYCARBOXYLATE WITH UREA; METAL ALKOXIDE; AROMATIC HYDROCARBON SOLVENT; BY-PRODUCT INHIBITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058819-A1 METHOD OF PRODUCING 2,4-OXAZOLIDINEDIONES AND METAL SALTS THEREOF HAO2, AOC2, HAO1 ALDH1A1 93/4885MEN1 3979/4885KMT2A 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.