Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624555 | 1.00 | CTSK (0.39) | CTSKCTSSCTSCCTSLCTSB | |
| SCHEMBL7624561 | 1.00 | CTSK (0.39) | CTSKCTSSCTSCCTSLCTSB | |
| SCHEMBL7615945 | 0.81 | MAPT (0.34) | — | |
| SCHEMBL7615942 | 0.81 | MAPT (0.34) | — | |
| SCHEMBL7615947 | 0.81 | MAPT (0.34) | — | |
| SCHEMBL7617300 | 0.81 | CAPN1 (0.34) | CTSS | |
| SCHEMBL7617304 | 0.81 | CAPN1 (0.34) | CTSS | |
| SCHEMBL7617309 | 0.81 | CAPN1 (0.34) | CTSS | |
| SCHEMBL2078726 | 0.78 | ZDHHC7 (0.33) | — | |
| SCHEMBL8507691 | 0.74 | CYP2C19 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620225-B1 | Cephalosporin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2002-11-13 | — | — | EP | disclosed |
| US-5523400-A | 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0620225-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-10-19 | — | — | EP | disclosed |