SCHEMBL7615947

SCHEMBL7615947

N#CCCNC(=O)[C@@H](Br)CCBr

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615942 1.00 MAPT (0.34) MAPTHSD17B10
SCHEMBL7615945 1.00 MAPT (0.34) MAPTHSD17B10
SCHEMBL7624554 0.81 CTSK (0.39)
SCHEMBL7624561 0.81 CTSK (0.39)
SCHEMBL7624555 0.81 CTSK (0.39)
SCHEMBL27340657 0.80 TSHR (0.41) MAPTHSD17B10
SCHEMBL4993506 0.71 SMN1; SMN2 (0.40)
SCHEMBL2078726 0.71 ZDHHC7 (0.33)
SCHEMBL14521485 0.71 KMT2A (0.41) MAPTHSD17B10
SCHEMBL7617309 0.70 CAPN1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620225-B1 Cephalosporin derivatives BASILEA PHARMACEUTICA AG (CH) 2002-11-13 EP disclosed
US-5523400-A 3-(PYRROLIDIN-3-YLIDENE=CH-),7-((2-AMINOTHIAZOL-4-YL)HYDROX -IMINOACETYLAMINO-)-3-CEPHEM DERIVATIVES; BROAD SPECTRUM ANTIBIOTICS HOFFMANN-LA ROCHE INC. (US) 1996-06-04 US disclosed
EP-0620225-A1 Cephalosporin derivatives F. HOFFMANN-LA ROCHE AG (CH) 1994-10-19 EP disclosed