Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 7/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049006 | 0.89 | MAPT (0.86) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL8049008 | 0.89 | MAPT (0.86) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6757890 | 0.83 | MAPT (0.75) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6756656 | 0.82 | MAPT (0.74) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6756657 | 0.82 | MAPT (0.74) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6756655 | 0.82 | MAPT (0.74) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6758014 | 0.78 | MAPT (0.68) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL6757872 | 0.78 | MAPT (0.68) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL7099543 | 0.78 | NR1H4 (0.70) | MAPTLMNAKMT2AMEN1NPC1 | |
| SCHEMBL25624793 | 0.78 | NFE2L2 (0.71) | MAPTLMNAKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444849-B1 | BACTERICIDES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-09-03 | — | — | US | disclosed |