Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626359 | 0.90 | — | — | |
| SCHEMBL7627855 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7623747 | 0.85 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7632600 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8412645 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL7621572 | 0.84 | GP6 (0.39) | AGTR1AGTR2 | |
| SCHEMBL7632644 | 0.84 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL4657793 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL7628580 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7630635 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451597-A | Hypotensive agents, congestive heart failure | G.D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | claimed |
| WO-1992015577-A1 | N-SUBSTITUTED (ALPHA-IMIDAZOLYL-TOLUYL) PYRROLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | claimed |
| US-6451833-B1 | ANGIOTENSIN ANTAGONISTS | PHARMACIA CORPORATION | 2002-09-17 | — | — | US | disclosed |
| US-6008368-A | USEFUL FOR TREATING HYPERTENSION AND CONGESTIVE HEART FAILURE; NONPEPTIDIC | G. D. SEARLE & CO. (US) | 1999-12-28 | — | — | US | disclosed |
| US-5451597-A | Hypotensive agents, congestive heart failure | G.D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5187271-A | Hypotensive agents, cardiovascular disorders | G. D. SEARLE & CO. (US) | 1993-02-16 | — | — | US | disclosed |
| WO-1992015577-A1 | N-SUBSTITUTED (ALPHA-IMIDAZOLYL-TOLUYL) PYRROLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |