Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630827 | 0.87 | KMT2A (0.46) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL7634952 | 0.87 | MMP2 (0.48) | MEN1KMT2AMAPTEPHX2PPARG | |
| SCHEMBL7634674 | 0.82 | SMN1; SMN2 (0.55) | MEN1KMT2AMAPTEPHX2PPARG | |
| SCHEMBL7626881 | 0.81 | HSP90AA1 (0.44) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL7627770 | 0.81 | MCHR1 (0.58) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL19922906 | 0.79 | MEN1 (0.52) | MEN1KMT2AMAPTEPHX2PPARG | |
| SCHEMBL7629877 | 0.78 | MMP2 (0.43) | MEN1KMT2AMAPTNPC1MMP2 | |
| SCHEMBL19922925 | 0.78 | MEN1 (0.51) | MEN1KMT2AMAPTEPHX2PPARG | |
| SCHEMBL10898232 | 0.77 | MEN1 (0.72) | MEN1KMT2AMAPTEPHX2RAB9A | |
| SCHEMBL7629870 | 0.76 | MMP2 (0.45) | MEN1KMT2ANPC1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907632-B1 | INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED PHENETHYL COMPOUNDS | BAYER AG (US) | 2002-12-11 | — | — | EP | disclosed |