Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627770 | 0.87 | MCHR1 (0.58) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7625129 | 0.87 | MEN1 (0.54) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7634674 | 0.86 | SMN1; SMN2 (0.55) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7630081 | 0.85 | MMP2 (0.50) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7625075 | 0.79 | MCHR1 (0.51) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7633774 | 0.79 | GCG (0.46) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7632375 | 0.78 | NPC1 (0.53) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7623455 | 0.78 | F10 (0.53) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7633124 | 0.77 | LMNA (0.50) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL13752658 | 0.77 | KMT2A (0.54) | MMP2MMP3MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907632-B1 | INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED PHENETHYL COMPOUNDS | BAYER AG (US) | 2002-12-11 | — | — | EP | disclosed |