7-Hydroxy Isoflavone

7-Hydroxy Isoflavone

SCHEMBL762528

O=c1c(-c2ccccc2)coc2cc(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 1.00
ALDH1A1 P00352 10/20 1.00
SMN1; SMN2 Q16637 8/20 1.00
NPC1 O15118 8/20 1.00
RAB9A P51151 8/20 1.00
POLB P06746 2/20 1.00
NPSR1 Q6W5P4 1/20 1.00
MAPT P10636 8/20 0.82
HPGD P15428 7/20 0.82
HSD17B10 Q99714 7/20 0.82
CYP3A4 P08684 5/20 0.82
TP53 P04637 5/20 0.82
CYP2D6 P10635 2/20 0.82
CYP2C9 P11712 2/20 0.82
MAOA P21397 2/20 0.82
MAOB P27338 2/20 0.82
CYP2C19 P33261 2/20 0.82
HDAC6 Q9UBN7 2/20 0.82
BLM P54132 2/20 0.82
CA12 O43570 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7-Hydroxy Isoflavone SCHEMBL5803559 0.97 KDM4E (0.94) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
Daidzein SCHEMBL2025991 0.93 KDM4E (0.86) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
Daidzein SCHEMBL21114371 0.90 KDM4E (1.00) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
Daidzein SCHEMBL19814 0.90 KDM4E (1.00) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
Daidzein SCHEMBL29374778 0.90 KDM4E (1.00) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL2069094 0.89 KDM4E (0.81) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL30527919 0.89 KDM4E (0.81) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL4173475 0.88 KDM4E (0.78) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL31135531 0.88 ALDH1A1 (0.78) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL14994916 0.88 ALDH1A1 (0.78) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854655-A Preparation method and application of 7-hydroxy isoflavone acetyl ferulate 武汉轻工大学 2023-10-10 CN claimed
CN-109400568-B 7-aryloxy acetoxyl isoflavone derivative and application thereof in pesticides 江苏大学 2022-10-25 CN claimed
CN-109400568-A 7- aroyl acetyl oxygroup isoflavone derivative and its application on pesticide 江苏大学 2019-03-01 CN claimed
CN-108358988-A A kind of preparation method of the glucoside of flavone compound 中国中医科学院中药研究所 2018-08-03 CN claimed
US-20180195957-A1 COLOR SENSOR PROTECTIVE LAYER POLESTAR TECHNOLOGIES, INC (US) 2018-07-12 US claimed
US-20180120276-A1 GAS MOLECULE SENSOR POLESTAR TECHNOLOGIES, INC. 2018-05-03 US claimed
CN-204918447-U Novel production of 7 - hydroxyl isoflavone device XINYI WANYU INDUSTRY AND TRADE CO LTD 2015-12-30 CN claimed
CN-103145674-B Crystal forms of 7-hydroxyl isoflavone, preparation methods thereof, pharmaceutical composition of methods and purpose INST MATERIA MEDICA CAMS 2015-04-22 CN claimed
CN-103087026-B Crystal form D of 7-hydroxyl isoflavone, preparation method of crystal form D and medicine composition and use of crystal form D INST MATERIA MEDICA CAMS 2015-01-28 CN claimed
CN-103121986-B Crystal form E of 7-hydroxyisoflavone and preparation method thereof, and pharmaceutical composition and application thereof INST MATERIA MEDICA CAMS 2015-01-28 CN claimed
EP-0941992-B1 Ipriflavone preparation process ERREGIERRE SPA (IT) 2002-05-08 EP claimed
US-5973169-A Ipriflavone preparation process ERREGIERRE S.P.A. (IT) 1999-10-26 US claimed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP claimed
WO-1998021946-A1 COMPOSITION AND TREATMENT FOR PERSISTENT REPRODUCTIVE TRANSITION SYMPTOMS INTERNUTRIA, INC. (US) 1998-05-28 WO claimed
EP-0620918-B1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL (GB) 1997-07-30 EP claimed
US-5480611-A Carbon dioxide detector GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC. 1996-01-02 US claimed
EP-0620918-A1 CARBON DIOXIDE DETECTOR. JOHNSON & JOHNSON PROFESSIONAL (GB) 1994-10-26 EP claimed
CN-1093086-A Isoflavone alicyclic hydrocarbon-ether and 9 oxime derivate thereof MATERIA MEDICA INST HUAXI MEDI (CN) 1994-10-05 CN claimed
WO-1993014399-A1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL PRODUCTS LTD. (GB) 1993-07-22 WO claimed
US-5229113-A Gene expression, soybeans LUBRIZOL GENETICS, INC. (US) 1993-07-20 US claimed