Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | RAB9A | P51151 | 6/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31135529 | 1.00 | ALDH1A1 (0.78) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL14994916 | 1.00 | ALDH1A1 (0.78) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9363043 | 0.98 | ALDH1A1 (0.76) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| 7-Hydroxy Isoflavone SCHEMBL762528 | 0.88 | KDM4E (1.00) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11739975 | 0.87 | NPC1 (0.62) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| 7-Hydroxy Isoflavone SCHEMBL5803559 | 0.85 | KDM4E (0.94) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Daidzein SCHEMBL2025991 | 0.84 | KDM4E (0.86) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL28075346 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11082015 | 0.83 | ALOX12 (0.77) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Isoflavone SCHEMBL3066716 | 0.82 | ALOX12 (0.80) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118726286-A | Isoflavone 6-hydroxylase, encoding gene and application thereof | 中国科学院遗传与发育生物学研究所 | 2024-10-01 | — | — | CN | disclosed |