Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627427 | 0.90 | PPARA (0.41) | PPARAPPARGPPARDGABRB1GABRB2 | |
| SCHEMBL7619657 | 0.90 | PPARA (0.41) | MAPTPPARAPPARGPPARDGABRB1 | |
| Benzoic Acid SCHEMBL6122914 | 0.90 | CTSK (0.44) | MAPTPPARAPPARGPPARDGABRB1 | |
| SCHEMBL8426063 | 0.89 | PPARA (0.41) | MAPTPPARAPPARGPPARDGABRB1 | |
| SCHEMBL7626209 | 0.88 | PPARA (0.41) | MAPTPPARAPPARGPPARDGABRB1 | |
| SCHEMBL6443317 | 0.87 | PPARA (0.48) | MAPTPPARAPPARGCTSSCTSK | |
| SCHEMBL8912015 | 0.87 | PPARA (0.46) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL767076 | 0.87 | CTSK (0.51) | MAPTPPARAPPARGPPARDGABRB1 | |
| SCHEMBL335777 | 0.87 | CTSK (0.51) | MAPTPPARAPPARGPPARDGABRB1 | |
| SCHEMBL6166 | 0.87 | CTSK (0.51) | MAPTPPARAPPARGPPARDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444825-B1 | CHEMICAL INTERMEDIATE FOR TAXOL | AVENTIS PHARMA S.A. (FR) | 2002-09-03 | — | — | US | disclosed |
| US-6043375-A | Process for the preparation of an oxazolidinecarboxylic acid which is useful for preparing therapeutically active taxoids | RHONE-POULENC RORER S.A. (FR) | 2000-03-28 | — | — | US | disclosed |