Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GMNN | O75496 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624414 | 0.92 | MEN1 (0.60) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL7772727 | 0.91 | MEN1 (0.57) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL7625979 | 0.80 | MEN1 (0.55) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL7621398 | 0.80 | MEN1 (0.55) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL7622230 | 0.80 | MEN1 (0.55) | MEN1KMT2AFAAHCYP1A2CYP2C19 | |
| SCHEMBL21708352 | 0.79 | ALOX5 (0.66) | KMT2AFAAHCYP1A2CYP2C19ALOX5 | |
| SCHEMBL21708270 | 0.79 | ALOX5 (0.66) | KMT2AFAAHCYP1A2CYP2C19ALOX5 | |
| SCHEMBL20534392 | 0.79 | ALOX5 (0.66) | KMT2AFAAHCYP1A2CYP2C19ALOX5 | |
| SCHEMBL20535104 | 0.79 | ALOX5 (0.66) | KMT2AFAAHCYP1A2CYP2C19ALOX5 | |
| SCHEMBL28863748 | 0.79 | ALOX5 (0.66) | KMT2AFAAHCYP1A2CYP2C19ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-0865422-B1 | USE OF AMINOALCOHOLDERIVATIVES AS DRUGS, DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |