Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622230 | 1.00 | MEN1 (0.55) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7621398 | 1.00 | MEN1 (0.55) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL4903668 | 0.81 | CYP1A2 (0.57) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL16244201 | 0.81 | CYP1A2 (0.57) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7625875 | 0.80 | MEN1 (0.57) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7771202 | 0.77 | FAAH (0.58) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7625967 | 0.77 | FAAH (0.58) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7620436 | 0.77 | FAAH (0.58) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7625854 | 0.77 | FAAH (0.58) | MEN1KMT2AFAAHSOAT1TP53 | |
| SCHEMBL7624338 | 0.77 | FAAH (0.58) | MEN1KMT2AFAAHSOAT1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-0865422-B1 | USE OF AMINOALCOHOLDERIVATIVES AS DRUGS, DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |