Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623785 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7624351 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7620597 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7623434 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7620605 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7619344 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7626538 | 0.90 | ALDH1A1 (0.44) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7629370 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7621344 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 | |
| SCHEMBL7624105 | 0.90 | FAAH (0.59) | ALDH1A1LMNACYP3A4SOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-0865422-B1 | USE OF AMINOALCOHOLDERIVATIVES AS DRUGS, DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ROCHE DIAGNOSTICS GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |