SCHEMBL7626372

SCHEMBL7626372

C[C](COC(C)(C)C)OOC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
KDM4E B2RXH2 1/20 0.47
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
MAPT P10636 5/20 0.45
LMNA P02545 3/20 0.44
F2 P00734 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.41
SLC1A5 Q15758 1/20 0.40
NPC1 O15118 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
EGFR P00533 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624126 0.91 TDP1 (0.57) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7636911 0.84 TDP1 (0.44) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7636383 0.84 SMN1; SMN2 (0.50) ALDH1A1TSHRSMN1; SMN2KDM4EPDCD1
SCHEMBL7637287 0.82 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7623941 0.82 CA1 (0.46) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7630626 0.81 CA1 (0.49) ALDH1A1HSD17B10TDP1KDM4EMAPT
SCHEMBL7632824 0.80 MAPT (0.56) ALDH1A1SMN1; SMN2KDM4EPDCD1CD274
SCHEMBL7629431 0.80 TSHR (0.37) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7637236 0.80 MEN1 (0.40) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL7625631 0.79 PLK1 (0.42) ALDH1A1TSHRHSD17B10TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed