SCHEMBL7629431

SCHEMBL7629431

C[C](COC(C)(C)C)OOC(=O)c1ccc([Si](C)(C)C)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 1/20 0.34
F2 P00734 1/20 0.33
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.31
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630091 0.85 NR1H2 (0.37) TSHRALDH1A1HSD17B10TDP1MAPK1
SCHEMBL7630817 0.85 ALDH1A1 (0.33) TSHRALDH1A1HSD17B10TDP1MAPK1
SCHEMBL7636911 0.84 TDP1 (0.44) TSHRALDH1A1HSD17B10TDP1MAPK1
SCHEMBL7627042 0.84 RAB9A (0.36) ALDH1A1TDP1F2LMNAHPGD
SCHEMBL7637287 0.82 ALDH1A1 (0.43) TSHRALDH1A1HSD17B10TDP1MAPK1
SCHEMBL7623941 0.82 CA1 (0.46) TSHRALDH1A1HSD17B10TDP1MAPK1
SCHEMBL7624126 0.82 TDP1 (0.57) TSHRALDH1A1HSD17B10TDP1MAPK1
SCHEMBL7630626 0.81 CA1 (0.49) ALDH1A1HSD17B10TDP1MAPK1LMNA
SCHEMBL7635551 0.81 ALDH1A1 (0.32) TSHRALDH1A1HSD17B10TDP1
SCHEMBL7635115 0.81 ALDH1A1 (0.32) TSHRALDH1A1HSD17B10TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed