Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427682 | 0.82 | TSHR (0.48) | ALDH1A1TSHRPOLBHDAC6CA1 | |
| SCHEMBL9615773 | 0.80 | RORC (0.43) | ALDH1A1TSHRPTPN1 | |
| SCHEMBL14378813 | 0.74 | TSHR (0.62) | ALDH1A1TSHRPOLBCA1CA2 | |
| SCHEMBL5199665 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRHDAC8CA1CA2 | |
| SCHEMBL2516876 | 0.72 | APP (0.58) | ALDH1A1TSHRHDAC6LMNAMAPT | |
| SCHEMBL9650220 | 0.71 | PPARG (0.49) | HDAC6LMNAPPARGPPARAHIF1A | |
| SCHEMBL28886036 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL10429631 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRPSMD14LMNAHIF1A | |
| SCHEMBL4460590 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRHDAC8PPARGPPARA | |
| SCHEMBL21527139 | 0.70 | TSHR (0.50) | ALDH1A1TSHRPOLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441112-B1 | TADDOL and titanium ( ) taddolate dendrimers and composition | NOVARTIS AG (CH) | 2002-08-27 | — | — | US | disclosed |
| US-6211316-B1 | Taddol and titanium (IV) taddolate dendrimers | NOVARTIS AG (CH) | 2001-04-03 | — | — | US | disclosed |