Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | ACP3 | P15309 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135956 | 0.85 | PNMT (0.65) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL22189207 | 0.83 | PNMT (0.56) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL2498815 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL1535283 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL1044909 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL29404730 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL343403 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL22193351 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL15792112 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL27743204 | 0.82 | PNMT (0.61) | PNMTCES2ACP3IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088077-A | (meth) acrylate compound, optical resin additive, optical element, and optical device | 株式会社尼康 | 2019-08-02 | — | — | CN | disclosed |
| CN-109503637-A | For treating the noval chemical compound of the disease of helminth | 安纳考尔医药公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-109153688-A | Oxaborolidine esters and uses thereof | 安纳考尔医药公司 | 2019-01-04 | — | — | CN | disclosed |
| US-6448295-B1 | TREATING CARDIOVASCULAR DISEASE; ATHEROSCLEROSIS, DYSLIPIDEMA HYPERCHOLESTEROLAEMIA; DECREASING CONCENTRATIONS OF LOW DENSITY LIPOPROTEIN AND RAISING LEVEL OF HIGH DENSITY LIPOPROTEIN | G.D. SEARLE & CO. | 2002-09-10 | — | — | US | disclosed |