Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.42 |
| ▸ | HMGCR | P04035 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620495 | 0.91 | PTPN7 (0.42) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL7623781 | 0.91 | CA2 (0.44) | CA1CA2KDM4EPOLBMAPT | |
| SCHEMBL7624349 | 0.91 | CA2 (0.44) | CA1CA2KDM4EPOLBMAPT | |
| SCHEMBL7625925 | 0.91 | CA2 (0.44) | CA1CA2KDM4EPOLBMAPT | |
| SCHEMBL7624494 | 0.88 | PTPN7 (0.39) | PTPN7HMGCRRECQLTDP1CA1 | |
| SCHEMBL7626038 | 0.86 | HMGCR (0.46) | PTPN7HMGCR | |
| SCHEMBL7620403 | 0.84 | PTPN7 (0.41) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL7620559 | 0.84 | PTPN7 (0.44) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL7622261 | 0.82 | FAAH (0.50) | PTPN7RECQLKDM4EMEN1USP2 | |
| SCHEMBL7621353 | 0.82 | FAAH (0.50) | PTPN7RECQLKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444832-B1 | OSTEOPOROSIS | ESSWEIN ANGELIKA (DE) | 2002-09-03 | — | — | US | disclosed |