SCHEMBL7626558

SCHEMBL7626558

COc1ccc(N(N)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.54
LTA4H P09960 2/20 0.52
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TRPA1 O75762 1/20 0.47
KMT2A Q03164 1/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10791254 0.98 CA4 (0.52) CA4LTA4HKDM4EHPGDCA12
SCHEMBL17461082 0.91 CA1 (0.58) CA4KDM4ECA12CA1CA2
SCHEMBL21787990 0.90 NPC1 (0.49) CA4LTA4HKDM4ETDP1ALDH1A1
SCHEMBL21787744 0.90 NPC1 (0.49) CA4LTA4HKDM4ETDP1ALDH1A1
Hydrochloric Acid SCHEMBL11274273 0.89 CA1 (0.55) CA4KDM4ECA12CA1CA2
SCHEMBL21787829 0.86 ABL1 (0.49) CA4LTA4HKDM4EHPGDKMT2A
SCHEMBL5675243 0.84 HSD17B2 (0.48) CA4CA12CA1CA2CA7
SCHEMBL24178006 0.83 CYP1A2 (0.57) CA4LTA4HKDM4ECA12CA1
SCHEMBL1078585 0.83 ACHE (0.65) HPGDCA12CA1CA2CA7
SCHEMBL9704374 0.82 PKM (0.61) CA2KMT2AMAPK1PGRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10566553-B2 Platinum complexes and devices ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-02-18 US disclosed
EP-1194409-A1 PYRAZOLIDINOL COMPOUNDS A-Viral AS (NO) 2002-04-10 EP disclosed
WO-2001000585-A1 PYRAZOLIDINOL COMPOUNDS A-VIRAL AS (NO) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10566553-B2 Platinum complexes and devices OXA1L, OCIAD1, OCIAD2 CA4 3823/4885LTA4H 2906/4885KDM4E 4835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.