Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398865 | 0.78 | QPCT (0.46) | ALDH1A1GLAHPGDQPCTQPCTL | |
| SCHEMBL7771667 | 0.75 | SLC2A1 (0.37) | ALDH1A1GLAHPGDSLC2A1GDA | |
| SCHEMBL7626879 | 0.74 | ALDH1A1 (0.46) | ALDH1A1F2GLAHPGDGDA | |
| SCHEMBL3179119 | 0.73 | KDM4E (0.30) | ALDH1A1GLAHPGD | |
| SCHEMBL5196384 | 0.72 | GDA (0.40) | GDA | |
| SCHEMBL4163924 | 0.71 | CNR2 (0.35) | QPCTQPCTL | |
| SCHEMBL30983864 | 0.70 | — | — | |
| SCHEMBL31269349 | 0.69 | HSD17B10 (0.33) | ALDH1A1GLAHPGDGDA | |
| SCHEMBL5349497 | 0.69 | HDAC6 (0.36) | ALDH1A1GLAHPGD | |
| SCHEMBL4436717 | 0.69 | HSD17B10 (0.33) | ALDH1A1GLAHPGDGDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107249-B | purine derivatives as A2A receptor agonists | NOVARTIS AG | 2010-10-13 | — | — | CN | disclosed |
| CN-100374454-C | 2-aminocarbonyl-9h-purine derivatives | HURI DRUG PLANT (US) | 2008-03-12 | — | — | CN | disclosed |
| CN-101107249-A | Purine derivatives as A2A receptor agonists | NOVARTIS AG (CH) | 2008-01-16 | — | — | CN | disclosed |
| CN-1810822-A | 2-aminocarbonyl-9h-purine derivatives | PFIZER (US) | 2006-08-02 | — | — | CN | disclosed |
| CN-1249074-C | 2-aminocarbonyl-9H-purine derivatives | PFIZER LTD (US) | 2006-04-05 | — | — | CN | disclosed |
| CN-1434830-A | 2-aminocarbonyl-9H-purine derivatives | PFIZER LTD (US) | 2003-08-06 | — | — | CN | disclosed |
| CN-1400975-A | Purine derivatives | PFIZER LTD (US) | 2003-03-05 | — | — | CN | disclosed |
| EP-1177202-A1 | 4'-C-ETHYNYL PURINE NUCLEOSIDES | YAMASA CORPORATION (JP) | 2002-02-06 | — | — | EP | disclosed |
| EP-1177201-A1 | 4'-C-ETHYNYL PYRIMIDINE NUCLEOSIDES | YAMASA CORPORATION (JP) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000069877-A1 | 4'-C-ETHYNYL PURINE NUCLEOSIDES | YAMASA CORPORATION (JP) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069876-A1 | 4'-C-ETHYNYL PYRIMIDINE NUCLEOSIDES | YAMASA CORPORATION (JP) | 2000-11-23 | — | — | WO | disclosed |