⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10135096 | 1.00 | — | — | |
| SCHEMBL16132612 | 1.00 | — | — | |
| SCHEMBL27850693 | 0.84 | APLNR (0.31) | — | |
| SCHEMBL13310480 | 0.79 | — | — | |
| SCHEMBL16086988 | 0.70 | — | — | |
| SCHEMBL27735 | 0.70 | — | — | |
| SCHEMBL16086835 | 0.70 | — | — | |
| SCHEMBL14204541 | 0.70 | — | — | |
| SCHEMBL11798683 | 0.69 | — | — | |
| SCHEMBL8737114 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663502-B2 | 2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease | LYCERA CORPORATION (US) | 2017-05-30 | — | — | US | claimed |
| US-20110065685-A1 | NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-03-17 | — | — | US | claimed |
| US-7560481-B2 | {1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl}(2,2,3,3-tetramethylcyclopropyl)methanone toluenesufonic acid salt; selectively target cannaboid B2 receptors; analgesics for both nociceptive and neuropathic pain; side effect reduction; immunology modulators; antiinflammatory agents; neuroprotectants | ABBOTT LABORATORIES (US) | 2009-07-14 | — | — | US | claimed |
| US-20070037801-A1 | {1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl}(2,2,3,3-tetramethylcyclopropyl)methanone toluenesufonic acid salt; selectively target cannaboid B2 receptors; analgesics for both nociceptive and neuropathic pain; side effect reduction; immunology modulators; antiinflammatory agents; neuroprotectants | ABBVIE INC. | 2007-02-15 | — | — | US | claimed |
| US-6624337-B1 | Fluorination of 1,1,2,2-tetrafluorocyclobutane in electrolytic cells, then thermocracking the perfluorocyclobutane in the presence of carbon or metals, to form chemical intermediates for fluoropolymers | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-09-23 | — | — | US | claimed |
| CN-1353681-A | Process for manufacture of fluoroolefins | DU PONT (US) | 2002-06-12 | — | — | CN | claimed |
| EP-1183223-A1 | PROCESS FOR THE MANUFACTURE OF FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-06 | — | — | EP | claimed |
| WO-2000075092-A1 | PROCESS FOR THE MANUFACTURE OF FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-14 | — | — | WO | claimed |
| US-12227721-B2 | Hydrofluorothioethers and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-02-18 | — | — | US | disclosed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| US-11932589-B2 | Hydrofluoroolefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-03-19 | — | — | US | disclosed |
| US-11858875-B2 | Propenylamines and methods of making and using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| WO-1994016739-A1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMACEUTICALS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| EP-0606252-A1 | FINE-CELLED PLASTIC FOAM CONTAINING HALOGENATED BLOWING AGENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5211873-A | Insulation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| US-5210106-A | Fine-celled plastic foam containing fluorochemical blowing agent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| WO-1993007201-A2 | FINE-CELLED PLASTIC FOAM CONTAINING HALOGENATED BLOWING AGENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-04-15 | — | — | WO | disclosed |
| EP-0321784-A2 | Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials | BAYER AG (DE) | 1989-06-28 | — | — | EP | disclosed |