SCHEMBL27735

SCHEMBL27735

CC1CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16086835 1.00
SCHEMBL16086988 1.00
Ammonia Solution, Strong SCHEMBL8355302 0.96
Bicarbonate SCHEMBL9660887 0.83 APLNR (0.38)
Formic Acid SCHEMBL28084719 0.80
SCHEMBL26237514 0.80
SCHEMBL10118996 0.78
SCHEMBL10250626 0.78
Carbamic Acid SCHEMBL9658814 0.78 ACHE (0.39)
SCHEMBL1744322 0.78 APLNR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118161500-A Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use 安进公司 2024-06-11 CN claimed
WO-2024064178-A1 HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE VMAT2 INHIBITORS AND METHODS OF USE NEUROCRINE BIOSCIENCES, INC. (US) 2024-03-28 WO claimed
CN-114728167-B Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use 安进公司 2024-03-19 CN claimed
WO-2024028169-A1 NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2024-02-08 WO claimed
US-20230416248-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-12-28 US claimed
US-20230365560-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-11-16 US claimed
WO-2023220219-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2023-11-16 WO claimed
US-20230365533-A1 BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2023-11-16 US claimed
CN-117062815-A VMAT2 inhibitors and methods of use 纽罗克里生物科学有限公司 2023-11-14 CN claimed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP claimed
EP-2102167-A2 SUBSTITUTED ARYLPYRAZOLES Pfizer Limited (GB) 2009-09-23 EP claimed
US-20080176865-A1 SUBSTITUTED ARYLPYRAZOLES PFIZER LIMITED (GB) 2008-07-24 US claimed
WO-2008072053-A2 SUBSTITUTED ARYLPYRAZOLES PFIZER LIMITED (GB) 2008-06-19 WO claimed
US-20070286842-A1 Organic Compounds and Their Uses NOVARTIS AG (CH) 2007-12-13 US claimed
US-20070149550-A1 1-aryl-4-cyclopropylpyrazoles with at least one fluorine attached to the cyclopropyl ring; parasiticides; fleas; extended duration of action for at least 28 days PFIZER INC. (US) 2007-06-28 US claimed
WO-1999033790-A1 INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS NIHON BAYER AGROCHEM K.K. (DE) 1999-07-08 WO claimed
EP-0398061-B1 Method of preparing alpha-fluoroacrylic acid derivatives and 1,1-difluoro-2-halogenoethyl(halogeno)methyl-ketones BAYER AG (DE) 1994-01-26 EP claimed
EP-0253175-B1 SUBSTITUTED FURAZANS BAYER AG (DE) 1992-12-30 EP claimed
US-5075494-A Process for the preparation of α-fluoroacrylic acid derivatives and new 1,1-difluoro-2-halogenoethyl (halogeno) methyl ketones BAYER AKTIENGESELLSCHAFT (DE) 1991-12-24 US claimed
EP-0253175-A2 Substituted furazans BAYER AG (DE) 1988-01-20 EP claimed