Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenylphosphine Oxide SCHEMBL27465043 | 0.84 | MEN1 (0.49) | ALDH1A1NPSR1L3MBTL1KCNH2SMN1; SMN2 | |
| Propane SCHEMBL372201 | 0.84 | TP53 (0.43) | LTA4HTP53ALDH1A1TSHRGLA | |
| Propane SCHEMBL1423596 | 0.84 | TP53 (0.43) | LTA4HTP53ALDH1A1TSHRGLA | |
| SCHEMBL9116127 | 0.82 | SMN1; SMN2 (0.33) | TP53ALDH1A1KDM4EL3MBTL1GLA | |
| Butane SCHEMBL2218261 | 0.81 | TP53 (0.41) | LTA4HTP53ALDH1A1TSHRKDM4E | |
| Propane SCHEMBL27484901 | 0.81 | TP53 (0.41) | LTA4HTP53ALDH1A1TSHRGLA | |
| Propane SCHEMBL28226117 | 0.81 | TP53 (0.41) | TP53ALDH1A1TSHRNPSR1GLA | |
| Propane SCHEMBL5024454 | 0.81 | TP53 (0.41) | TP53ALDH1A1TSHRNPSR1GLA | |
| Butane SCHEMBL3883260 | 0.81 | TP53 (0.41) | LTA4HTP53ALDH1A1TSHRKDM4E | |
| Propane SCHEMBL27693170 | 0.81 | TP53 (0.41) | LTA4HTP53ALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055582-A | Synthesis of nickel and palladium organophosphorus complexes | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-25 | — | — | US | claimed |
| US-6441233-B1 | CARBONYLATION, AMIDATION; IN PRESENCE OF ACYLATION CATALYST | SOLVIAS AG (CH) | 2002-08-27 | — | — | US | disclosed |
| EP-1140796-A1 | PROCESS FOR THE PREPARATION OF AROMATIC CARBOXYLIC ACID AMIDES | Solvias AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037428-A1 | PROCESS FOR THE PREPARATION OF AROMATIC CARBOXYLIC ACID AMIDES | SOLVIAS AG (CH) | 2000-06-29 | — | — | WO | disclosed |