SCHEMBL762778

SCHEMBL762778

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(-c4c5ccccc5c5c6c(cccc46)-c4cc(N(c6ccccc6)c6ccccc6)ccc4-5)c4cccc-3c24)cc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021051 0.87 MAPT (0.33) ENPP1
SCHEMBL25043499 0.87 KDM4E (0.33)
SCHEMBL13085095 0.83 MCL1 (0.32) ENPP1
SCHEMBL763010 0.82 PTPRC (0.35)
SCHEMBL15762800 0.82 CRHBP (0.35)
SCHEMBL12032229 0.82 ENPP1 (0.35) ENPP1
SCHEMBL4078983 0.82 ENPP1 (0.35) ENPP1
SCHEMBL762745 0.81 ALDH1A1 (0.35)
SCHEMBL15097041 0.81 TDP1 (0.32)
SCHEMBL12032283 0.80 ENPP1 (0.35) ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138668-B2 Benzo[a]fluoranthene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2012-03-20 US disclosed
US-8138668-B2 Benzo[a]fluoranthene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2012-03-20 US disclosed
US-20100019661-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed
US-20100019661-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2010-01-28 US disclosed
WO-2008140134-A1 BENZO[A]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100019661-A1 BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME AFF1, AFF2, CYP1A1 ENPP1 4456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.