Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480112 | 0.89 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7625417 | 0.80 | MEN1 (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6137022 | 0.80 | HSD17B10 (0.56) | MEN1KMT2AALDH1A1CLCN2POLB | |
| SCHEMBL7624852 | 0.78 | IDO1 (0.47) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27895010 | 0.74 | HSD17B10 (0.38) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL18716699 | 0.74 | POLB (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10727224 | 0.73 | POLB (0.39) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28389064 | 0.73 | RORC (0.40) | MEN1KMT2AALDH1A1POLBHSD17B10 | |
| SCHEMBL28909042 | 0.72 | NPC1 (0.47) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28389058 | 0.72 | IAPP (0.43) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451734-B1 | Substituted 3-benzylpyrazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |