SCHEMBL7628279

SCHEMBL7628279

Cc1sc2cncn2c1C1=C(C(=O)O)N2C(=O)[C@H]([C@@H](C)O)[C@H]2[C@H]1C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 15/20 0.40
TDO2 P48775 13/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628267 0.87 IDO1 (0.36) IDO1TDO2
SCHEMBL6887719 0.83 CACNA1C (0.34) IDO1TDO2
SCHEMBL7627107 0.82 CACNA1C (0.34) IDO1TDO2
SCHEMBL7630479 0.81 CACNA1C (0.34)
SCHEMBL8195457 0.80 PLCG1 (0.38) IDO1TDO2
SCHEMBL7631777 0.79 IDO1 (0.40) IDO1TDO2
SCHEMBL6801499 0.79 CACNA1C (0.34)
SCHEMBL7635372 0.76 CACNA1C (0.34)
SCHEMBL7728385 0.76 ABCC2 (0.34) IDO1TDO2
SCHEMBL7628803 0.75 FAP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022279-B1 NEW CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA (JP) 2002-09-04 EP disclosed
US-6310056-B1 2-SUBSTITUTED WITH A IMIDAZO(5,1-B)THIAZOLE GROUP; TREATING INFECTIONS, INCLUDING ANTIBIOTIC RESISTANT BACTERIAL INFECTIONS MEIJI SEIKA KAISHA, LTD. (JP) 2001-10-30 US disclosed
EP-1022279-A1 NEW CARBAPENEM DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 2000-07-26 EP disclosed