Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105088 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPK1LMNAMAPTHPGD | |
| SCHEMBL28045277 | 0.81 | TUBB4A (0.47) | SMN1; SMN2AOC3TUBB1MAPTHPGD | |
| SCHEMBL11104763 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1LMNAMAPTHPGD | |
| SCHEMBL2001469 | 0.77 | L3MBTL1 (0.58) | SMN1; SMN2MAPK1LMNAMAPTHPGD | |
| SCHEMBL3674074 | 0.76 | CA9 (0.50) | SMN1; SMN2AOC3MAPTHPGDKMT2A | |
| SCHEMBL30701949 | 0.76 | CA9 (0.50) | SMN1; SMN2AOC3MAPTHPGDKMT2A | |
| SCHEMBL5841179 | 0.76 | PLAU (0.48) | SMN1; SMN2AOC3TUBB1MAPK1LMNA | |
| SCHEMBL6608879 | 0.75 | CA12 (0.61) | SMN1; SMN2LMNAMAPTHPGDMEN1 | |
| SCHEMBL6475127 | 0.75 | L3MBTL1 (0.65) | SMN1; SMN2MAPK1LMNAMAPTHPGD | |
| SCHEMBL2591219 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2AOC3MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399658-B1 | REDUCING DRUG SIDE EFFECT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1004304-A1 | COMPOSITION CONTAINING ASCORBIC ACID | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |