Bromide

Bromide

SCHEMBL7628516

C[N+]1(CCCC[N+]2(C)CCCC2)CCCC1.[Br-].[Br-]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.40
CHRM4 known ✓ P08173 1/20 0.40
CHRM5 known ✓ P08912 1/20 0.40
CHRM1 known ✓ P11229 1/20 0.40
CHRM3 known ✓ P20309 1/20 0.40
BBOX1 O75936 2/20 0.56
LMNA P02545 4/20 0.48
APOBEC3A P31941 2/20 0.48
APOBEC3G Q9HC16 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.43
TP53 P04637 1/20 0.41
CHRNA7 P36544 1/20 0.35
GNAI3 P08754 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7605138 0.97 BBOX1 (0.54) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Bromide SCHEMBL14913825 0.97 BBOX1 (0.54) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Bromide SCHEMBL7593947 0.97 BBOX1 (0.54) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Bromide SCHEMBL250430 0.97 BBOX1 (0.54) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
SCHEMBL812356 0.97 BBOX1 (0.58) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Bromide SCHEMBL14914407 0.94 LMNA (0.55) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Bromide SCHEMBL14914316 0.94 LMNA (0.55) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Water SCHEMBL20472801 0.94 BBOX1 (0.56) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
Bromide SCHEMBL8910745 0.94 BBOX1 (0.56) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A
SCHEMBL12638424 0.94 BBOX1 (0.56) BBOX1LMNAAPOBEC3AAPOBEC3GKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825152-B1 Zeolite NU-88, method for its preparation and its catalytic uses INST FRANCAIS DU PETROLE (FR) 2002-01-23 EP claimed
US-6027707-A BASED ON SILICON OR GERMANIUM OXIDE AND OXIDES OF ALUMINUM, IRON, GALLIUM, BORON, TITANIUM, VANADIUM, ZIRCONIUM, MOLYBDENUM, ARSENIC, ANTIMONY, CHROMIUM AND/OR MANGANESE; HYDROREFINING CATALYSTS; HYDROCARBON CONVERSIONS INSTITUT FRANCAIS DU PETROLE (FR) 2000-02-22 US claimed
US-6027707-A BASED ON SILICON OR GERMANIUM OXIDE AND OXIDES OF ALUMINUM, IRON, GALLIUM, BORON, TITANIUM, VANADIUM, ZIRCONIUM, MOLYBDENUM, ARSENIC, ANTIMONY, CHROMIUM AND/OR MANGANESE; HYDROREFINING CATALYSTS; HYDROCARBON CONVERSIONS INSTITUT FRANCAIS DU PETROLE (FR) 2000-02-22 US disclosed