Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CALML3 | P27482 | 1/20 | 0.48 |
| ▸ | SDHA | P31040 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 7/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143030 | 0.84 | F10 (0.40) | LGMNMAOBMAOAF10ITGB3 | |
| SCHEMBL6058747 | 0.83 | MAOA (0.71) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6058753 | 0.83 | MAOA (0.71) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6616153 | 0.81 | MAOB (0.54) | LGMNMAOBMAOALMNAPTGS1 | |
| SCHEMBL8143032 | 0.81 | MAOB (0.54) | LGMNMAOBMAOALMNAPTGS1 | |
| SCHEMBL8796264 | 0.81 | MAOB (0.51) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6764368 | 0.81 | TOP2B (0.55) | MAOBMAOALMNA | |
| SCHEMBL6759903 | 0.80 | TOP2B (0.67) | MAOBLMNA | |
| SCHEMBL2089026 | 0.78 | MAOB (0.53) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6988167 | 0.78 | MAOB (0.48) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212058-A1 | TOPICAL TREATMENT FOR PREVENTION OF OCULAR INFECTIONS | INSITE VISION INCORPORATED (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019366-A1 | TOPICAL TREATMENT FOR PREVENTION OF OCULAR INFECTIONS | INSITE VISION INCORPORATED (US) | 2001-03-22 | — | — | WO | disclosed |
| EP-1019385-A1 | AMINOARYL OXAZOLIDINONE N-OXIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997010223-A1 | AMINOARYL OXAZOLIDINONE N-OXIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-20 | — | — | WO | disclosed |
| EP-0750618-A1 | OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025106-A1 | OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1995-09-21 | — | — | WO | disclosed |